Lab Github: https://github.com/tellierlab

All the genome-wide data are accessible on the following links from the GEO database: 

GSE221279: Isoginkgetin and Madrasin are poor splicing inhibitors. PLOS One. 2024

GSE219008: Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signaling pathway. Molecular Cell. 2024.

GSE148581: APOBEC3B regulates R-loops and promotes transcription-associated mutagenesis in cancer. Nature Genetics. 2023.

GSE176541: CDK9 and PP2A regulate RNA polymerase II transcription termination and coupled RNA maturation. EMBO Reports. 2022.

GSE146970: RNase H2, mutated in Aicardi‐Goutières syndrome, resolves co-transcriptional R-loops to prevent DNA breaks and inflammation. Nature Communications. 2022.

GSE197372: CAPTURE of the Human U2 snRNA Genes Expands the Repertoire of Associated Factors. Biomolecules. 2022.

GSE167060: Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease. Molecular Cell. 2021.

GSE147055: The 7SK/P-TEFb snRNP controls ultraviolet radiation-induced transcriptional reprogramming. Cell Reports. 2021.

GSE115290: CDK12 globally promotes RNA polymerase II transcription elongation and carboxyl-terminal domain phosphorylation. Nucleic Acids Research, 2020.

GSE99955: Effect of CFIm68 knockdown on RNA polymerase II transcription. BMC Research Notes, 2019.

GSE129870: The roles of the human SETMAR (Metnase) protein in illegitimate DNA recombination and non-homologous end joining repair. DNA Repair, 2019.

GSE108773: Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome. Nucleic Acids Research, 2019.

GSE119712: Effect of CFIm25 knockout on RNA polymerase II transcription. BMC Research Notes, 2018.

GSE110028: Deregulated Expression of Mammalian lncRNA through Loss of SPT6 Induces R-Loop Formation, Replication Stress, and Cellular Senescence. Molecular Cell, 2018.

All the proteomics data are accessible on the following links from the PRIDE database:

CDK9 inhibition phosphoproteomics: PXD026720, CDK9 and PP2A regulate RNA polymerase II transcription termination and coupled RNA maturation. EMBO Reports. 2022.

SF3B1 interactome: PXD033694, CDK9 and PP2A regulate RNA polymerase II transcription termination and coupled RNA maturation. EMBO Reports. 2022.