For an automatically updated version, check Google Scholar, ORCID, or PubMed. PDF version of the papers are accessible on ResearchGate or you can contact me by email.
*, # equal authorship, ** corresponding authorship
Preprint papers:
C) Nakayama C, Daigaku Y, Aoi Y, Fang Q, Kimura H, Shilatifard A, Tellier M**, Nojima T**. NELF coordinates Pol II transcription termination and DNA replication initiation. bioRxiv. 2024
B) Tellier M**, Ansa G, Murphy S**. Differential effects of pre-mRNA splicing inhibitors on RNA polymerase II transcription. bioRxiv. 2023.
A) Hardy JG, Tellier M, Murphy S, Norbury CJ. The RS Domain of Human CFIm68 Plays a Key Role in Selection Between Alternative Sites of Pre-mRNA Cleavage and Polyadenylation. bioRxiv. 2017.
Published papers:
33) Dulloo I, Tellier M, Levet C, Chikh A, Zhang B, Blaydon CD, Webb CM, Kelsell DP, Freeman M. Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signaling pathway. Molecular Cell. 2024.
32) McCann JL*, Cristini A*, Law EK, Yun Lee S, Tellier M, Carpenter MA, Beghe C, Jin Kim J, Jarvis MC, Stefanovska B, Temiz NA, Bergstrom EN, Salamango DJ, Brown MR, Murphy S, Alexandrov LB, Miller KM, Gromak N, Harris RS. APOBEC3B regulates R-loops and promotes transcription-associated mutagenesis in cancer. Nature Genetics. 2023
31) Henfrey C, Murphy S, Tellier M**. Regulation of mature mRNA levels by RNA processing efficiency. NAR Genomics and Bioinformatics. 2023.
30) Wilton J, Lopes de Mendonça F, Pereira-Castro I, Tellier M, Nojima T, Costa AM, Freitas J, Murphy S, Oliveira MJ, Proudfoot NJ, Moreira A. Pro-inflammatory polarization and colorectal cancer modulate alternative and intronic polyadenylation in primary human macrophages. Frontiers in Immunology. 2023
29) Akama-Garren EH, Miller P, Carroll TM, Tellier M, Sutendra G, Buti L, Zaborowska J, Goldin RD, Slee E, Szele FG, Murphy S, Lu X. Regulation of immunological tolerance by the p53-inhibitor iASPP. Cell Death & Disease. 2023.
28) Moussawi K*, Chung K*, Carroll TM*, Osterburg C*, Smirnov A*, Lotz R, Miller P, Dedeic Z, Zong S, Oti M, Kouwenhoven EN, Asher R, Golding R, Tellier M, Murphy S, Zhou H, Dotsch V, Lu X. Mutant Ras and inflammation-driven skin tumorigenesis is suppressed via a JNK-iASPP-AP1 axis. Cell Reports. 2022
27) Tellier M**, Zaborowska J, Neve J, Nojima T, Hester S, Fournier M, Furger A, Murphy S**. CDK9 and PP2A regulate the link between RNA polymerase II transcription termination and RNA maturation. EMBO Reports. 2022.
26) Cristini A, Tellier M, Constantinescu F, Accalai C, Albulescu LO, Heiringhoff R, Bery N, Sordet O, Murphy S, Gromak N. RNase H2, mutated in Aicardi‐Goutières syndrome, resolves co-transcriptional R-loops to prevent DNA breaks and inflammation. Nature Communications. 2022.
25) Guiro J*, Fagbemi M*, Tellier M, Zaborowska J, Barker S, Fournier M, Murphy S. CAPTURE of the Human U2 snRNA Genes Expands the Repertoire of Associated Factors. Biomolecules. 2022.
24) Tellier M**. Structure, Activity, and Function of SETMAR Protein Lysine Methyltransferase. Life, 2021
23) Wilton J, Tellier M, Nojima T, Costa AM, Oliveira MJ, Moreira A. Simultaneous studies of gene expression and alternative polyadenylation in primary human immune cells. Methods in Enzymology. 2021.
22) Prokhorova E*, Agnew T*, Wondisford AR, Tellier M, Kaminski N, Beijer D, Holder J, Groslambert J, Suskiewicz MJ, Zhu K, Reber JM, Krassnig SC, Palazzo L, Murphy S, Nielsen ML, Mangerich A, Ahel D, Baets J, O’Sullivan RJ, Ahel I. Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease. Molecular Cell. 2021.
21) Studniarek C, Tellier M, Martin P, Murphy S, Kiss T, Egloff S. The 7SK/P-TEFb snRNP controls ultraviolet radiation-induced transcriptional reprogramming. Cell Reports. 2021.
20) Rodrigues PRS*, Alrubayyi A*, Pring E*, Bart V*, Jones R*, Coveney C, Lu F, Tellier M, Maleki-Toyserkani S, Richter FC, Scourfield O, Gea-Mallorqui E, Davies CL, and The Oxford-Cardiff COVID19 Literature Consortium. Innate immunology in COVID-19 – A LIVING REVIEW PART II: Dysregulated inflammation drives immunopathology. Oxford Open Immunology, 2020.
19) Coveney C*, Tellier M*, Lu F*, Maleki-Toyserkani S*, Jones R, Bart V, Pring E, Alrubayyi A, Richter FC, Scourfield O, Rehwinkel J, Rodrigues PRS, Davies CL, Gea-Mallorqui E, and The Oxford-Cardiff COVID19 Literature Consortium. Innate immunology in COVID-19 – A LIVING REVIEW PART I: Viral entry, sensing and evasion. Oxford Open Immunology, 2020.
18) Tellier M**, Murphy S. Incomplete removal of ribosomal RNA can affect chromatin RNA-seq data analysis. Transcription, 2020.
17) Lu F*,**, Tellier M*,**. CRISPRing for host genes regulating SARS-CoV-2. Nature Reviews Immunology, 2020.
16) Tellier M*,**, Zaborowska J*, Caizzi L, Mohammad E, Velychko T, Schwalb B, Ferrer-Vicens I, Blears D, Nojima, T, Cramer P, Murphy S**. CDK12 globally promotes RNA polymerase II transcription elongation and carboxyl-terminal domain phosphorylation. Nucleic Acids Research, 2020.
15) Tellier M*, Maudin I*, Murphy S. Transcription and splicing: a two-way street. WIREs RNA, 2020.
14) Tellier M**, Chalmers R**. Compensating for over-production inhibition of the Hsmar1 transposon in Escherichia coli using a series of constitutive promoters. Mobile DNA, 2020.
13) Tellier M**, Hardy JG, Norbury CJ, Murphy S. Effect of CFIm68 knockdown on RNA polymerase II transcription. BMC Research Notes, 2019.
12) Tellier M**, Chalmers R**. The roles of the human SETMAR (Metnase) protein in illegitimate DNA recombination and non-homologous end joining repair. DNA Repair, 2019.
11) Tellier M**, Chalmers R. Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome. Nucleic Acids Research, 2019.
10) Tellier M**, Hardy JG, Norbury CJ, Murphy S. Effect of CFIm25 knockout on RNA polymerase II transcription. BMC Research Notes, 2018.
9) Nojima T*, Tellier M*, Foxwell J, Rebeiro de Almeida C, Tan Wong SM, Dhir S, Dhir A, Murphy S, Proudfoot NJ. Deregulated Expression of Mammalian lncRNA through Loss of SPT6 Induces R-Loop Formation, Replication Stress, and Cellular Senescence. Molecular Cell, 2018.
8) Blundell-Hunter G, Tellier M, Chalmers R. The role of subunit-architecture in the regulation of prokaryotic and eukaryotic transposons and its relationship to genome size. Nucleic Acids Research, 2018.
7) Bauer DLV, Tellier M, Martinez-Alonso M, Nojima T, Proudfoot NJ, Murphy S, Fodor E. A two-pronged attack on RNA polymerase II transcription by influenza virus. Cell Reports 2018.
6) Wood K*, Tellier M*,**, Murphy S**. The role of DOT1L in transcription and genomic stability. Biomolecules. 2018.
5) Egloff S, Vitali P, Tellier M, Raffel R, Murphy S, Kiss T. The 7SK snRNP associates with the little elongation complex to promote snRNA gene expression. EMBO Journal. 2017.
4) Tellier M*, Ferrer-Vicens I*, Murphy S. The point of no return: The poly(A)-associated elongation checkpoint. RNA Biology. 2016.
3) Laitem C, Zaborowska J, Tellier M, Yamaguchi Y, Cao Q, Egloff S, Handa H, Murphy S. CTCF regulates NELF, DSIF and P-TEFb recruitment during transcription. Transcription. 2015.
2) Tellier M, Bouuaert CC, Chalmers R. Mariner and the ITm Superfamily of Transposons. Microbiology Spectrum. 2015.
1) Bouuaert CC, Tellier M, Chalmers R. One to rule them all: A highly conserved motif in mariner transposase controls multiple steps of transposition. Mobile Genetics Elements. 2014.